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Genetic Polymorphisms in the TATA box and Upstream Phenobarbital-Responsive Enhancer Module of the UGT1A1 Promoter Have Combined Effects on UGT1A1 Transcription Mediated by CAR, PXR, or GR in Human Liver
Drug Metabolism and Disposition, 06/19/09
Li Y et al. - The combined genotypes containing A(TA)7TAA and -3279G decrease UGT1A transcription mediated by CAR, PXR, or GR, but not by HNF1 alpha or HNF4 alpha.
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Expert Opinion on Investigational Drugs, 12/15/09
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