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A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain
Current Medical Research and Opinion, 06/29/09
Daniels S et al. - Clinically meaningful and statistically significant improvements were observed with tapentadol IR 50mg and 75mg compared with placebo for the relief of moderate-to-severe acute pain after orthopedic surgery. Tapentadol IR 50mg and 75mg were non-inferior to oxycodone HCl IR 10mg for the treatment of acute pain based on the primary efficacy endpoint of SPID48 and the pre-specified margin of 48 points.
Today in Drug Interactions...keeping you current
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A Randomized, Double-Blind Study Examining the Comparative Efficacies and Safety of Inhaled Epinephrine and Nasal Decongestant in Hospitalized Infants With Acute Bronchiolitis
The Pediatric Infectious Disease Journal, 11/17/09
Nifekalant versus lidocaine for in-hospital shock-resistant ventricular fibrillation or tachycardia
Resuscitation, 11/18/09
Effects of clozapine and olanzapine on cortical thickness in childhood-onset schizophrenia
Schizophrenia Research, 11/17/09
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Doxycycline for osteoarthritis of the knee or hip
Cochrane Reviews, 10/23/09
Effect of Rosiglitazone, Metformin, and Glyburide on Bone Biomarkers in Patients with Type 2 Diabetes
Journal of Clinical Endocrinology and Metabolism, 11/10/09
A New Drug in a New Class for Postmenopausal Osteoporosis
The Female Patient, 11/11/09
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