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Finn AV et al. - The authors need to be able to understand in living patients the histologic characteristics of non-flow limiting lesions and how these relate to risk for future events. Moreover, authors also need to be able to modify critical elements within the atherosclerotic plaque, specifically macrophage foam cells, neoangiogenesis, necrotic core size, and fibrous cap thickness. These advancements will require newer pharmacologic agents and clinical refinements in the monitoring of treatment effects.


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