Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Statins and cancer risk
Your Article Summary
See Latest ArticlesNicotinic acetylcholine receptors at atomic resolution
Current Opinion in Pharmacology , 06/17/09
Tsetlin V et al. - While the structures of several G protein coupled receptors have been solved by X-ray crystallography, the high-resolution structure of first ligand-gated ion channels has been available only recently. The ultrastructure of the prototypic LGIC nAChR is deduced from electron microscopy in combination with crystal structures of model proteins. From this analysis, agonist and antagonist binding sites and hints at the mechanism of channel gating become visible.
Today in Basic Science...keeping you current
Receive free subspecialty "5-minute updates" via email
No evidence for functional selectivity of proxyfan at the human histamine H3-receptor coupled to defined Gi/Go protein heterotrimers
Journal of Pharmacology and Experimental Therapeutics, 12/04/09
Metabolic Fate of Lactoferricin Based Antimicrobial Peptides: Effect of Truncation and Incorporation of Amino Acid Analogs on the in vitro Metabolic Stability
Journal of Pharmacology and Experimental Therapeutics, 12/04/09
Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis
Journal of Pharmacology and Experimental Therapeutics, 12/04/09
Sponsor
Article Search
Sponsor