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See Latest ArticlesEffect of membrane cholesterol on BSEP/Bsep activity - species specificity studies for substrates and inhibitors
Drug Metabolism and Disposition, 06/12/09
Kis E et al. - The cholesterol-loaded Sf9 vesicles overexpressing BSEP/Bsep appears to be a useful system for the identification of potential cholestatic compounds and can also be used for the investigation of species specificity. The authors observed greater differences in IC50 values for inhibitors than in KM values for substrates between species.
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UGT1A10: Activity against the tobacco-specific nitrosamine, NNAL, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility
Drug Metabolism and Disposition, 12/14/09
Glucuronidation of Psilocin and 4-Hydroxyindole by the Human UDP-glucuronosyltransferases
Drug Metabolism and Disposition, 12/14/09
Glucuronidation of Dihydrotestosterone and Trans-androsterone by Recombinant UGT1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
Drug Metabolism and Disposition, 12/14/09
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