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Olanzapine/fluoxetine combination vs. lamotrigine in the 6-month treatment of bipolar I depression
International Journal of Neuropsychopharmacology, 06/11/09
Brown E et al. - Patients with bipolar I depression had significantly greater symptom improvement over 25 wk on OFC compared with Lam. There was no treatment difference in incidence of relapse. OFC-treated patients had more treatment-emergent adverse events and greater incidence of weight gain and hypercholesterolaemia.
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