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Cytochrome P450 2C9 Variants Influence Response to Celecoxib for Prevention of Colorectal Adenoma
Gastroenterology, 06/10/09
Chan AT et al. - The greater efficacy of high-dose celecoxib, compared with the low-dose, in preventing colorectal adenoma appears confined to individuals with slow metabolizer genotypes. Genetic variability influences susceptibility to the potential benefits and hazards of celecoxib.
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