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Regulatory and Study Conditions for the Determination of Bioequivalence of Highly Variable Drugs
Journal of Pharmacy and Pharmaceutical Sciences, 05/21/09
Endrenyi L et al. - The condition of CVS = CV0 = 30% and PE/GMR = 0.80-1.25 is recommended as a composite regulatory criterion. With alternative settings of the conditions, such as the recommended CV0 = 25% and/or PE/GMR = 0.87-1.15, the composite criterion would reflect almost entirely the GMR point estimate. This would be an undesirable outcome.
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Opiate-induced hypernociception and chemokine receptors
Neuropharmacology, 11/10/09
Ketorolac But Not Morphine Exerts Inflammatory and Metabolic Effects in Synovial Membrane After Knee Arthroscopy: A Double-Blind Randomized Prospective Study Using the Microdialysis Technique
Regional Anesthesia and Pain Medicine, 11/04/09
Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1
Current Drug Targets, 11/03/09
Today in Major Studies...keeping you current
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Carboplatin-Pemetrexed Adjuvant Chemotherapy in Resected Non-small Cell Lung Cancer (NSCLC): A Phase II Study
Anticancer Research, 11/16/09
Pivotal Data Published in the Journal Cancer Demonstrate that TREANDA Induced Durable Responses in Relapsed Indolent Non-Hodgkins Lymphoma
Cephalon, 11/06/09
Mycophenolate mofetil: An update
Drugs of Today, 11/05/09
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