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Eosinophil-selective binding and pro-apoptotic effect of a synthetic Siglec-8 ligand, polymeric 6'-sulfated sialyl Lewis X in vitro
Journal of Pharmacology and Experimental Therapeutics, 05/20/09
Hudson SA et al. - These data demonstrate that a soluble, multivalent glycan selectively binds to human eosinophils and induces their apoptosis in vitro, and provide proof-of-concept that such as reagent could be used to selectively target eosinophils.
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Evaluation of Treatment Satisfaction in Children with Allergic Disease Treated with an Antihistamine: An International, Non-Interventional, Retrospective Study
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