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Identification, Ki determination and CoMFA analysis of nuclear receptor ligands as competitive inhibitors of OATP1B1-mediated estradiol-17 beta-glucuronide transport
Pharmacological Research , 05/21/09
Gui C et al. - The CoMFA results indicate that the substrate binding site of OATP1B1 consists of a large hydrophobic middle part with basic residues at both ends that could be very important for substrate binding.
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The role of CGRP in the pathophysiology of migraine and efficacy of CGRP receptor antagonists as acute antimigraine drugs
Pharmacology & Therapeutics, 12/16/09
The asymmetric/symmetric activation of GPCR dimers as a possible mechanistic rationale for multiple signalling pathways
Trends in Pharmacological Sciences, 12/15/09
UGT1A10: Activity against the tobacco-specific nitrosamine, NNAL, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility
Drug Metabolism and Disposition, 12/14/09
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