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In a study of an extended follow up of 290 women naive to HPV type 16, the HPV 16 component of GARDASIL was efficacious against HPV 16 infection for an average of 8.5 years after administration. The women enrolled in this study are a subset of the original Phase II HPV 16 proof-of-concept study published in 2002. Follow up ranged from 7.2 years to up to 9.5 years.

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