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See Latest ArticlesImpaired function of GABAB receptors in tissues from pharmacoresistant epilepsy patients
Epilepsia, 04/29/09
Teichgraber LA et al. - The small IPSPB, baclofen-conductances, and paired-pulse depression of PDSs and IPSPs in human TLE tissue indicate a reduced density of post- and presynaptic GABAB receptors. The reduced efficacy of presynaptic GABAB receptors facilitates the occurrence of repetitive synaptic activity.
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