Pharmacy Medical News about gonorrhea

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The use of cephalosporins for gonorrhea: the impending problem of resistance
Expert Opinion in Pharmacotherapy, 03/17/09

Barry PM et al. - The mechanism of this resistance seems to be associated with a mosaic penicillin binding protein in addition to other chromosomal mutations previously found to confer resistance to beta-lactam antimicrobials. Few good options exist or are in development for treating cephalosporin-resistant isolates, as most have had multidrug resistance. Preventing the spread of resistant isolates will depend on ambitious antimicrobial management programs, strengthening and expanding surveillance networks, and through effective sexually transmitted disease control and prevention.

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