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Mucoadhesive Polymeric Hydrogels for Nasal Delivery of Acyclovir
Drug Development and Industrial Pharmacy, 02/25/09
Alsarra IA et al. - The release rate of drug from PVP gels was increased further in presence of PEG or glycerol. Histopathological investigations proved that the PVP was a safe hydrogel to be used for mucosal delivery. The PEG in gel formulations caused less damages to the nasal mucosal compared to formulation containing glycerol.
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