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See Latest ArticlesReview of recombinant human deoxyribonuclease (rhDNase) in the management of patients with cystic fibrosis
Biologics: targets & therapy, 12/11/08
Pressler T - The most important problem in cystic fi brosis (CF) lung disease is chronic airway inflammation and infection, which starts early in life. To prevent severe lung damage, it is important to mobilize as much sputum as possible from the lung on a daily basis. RhDNase is an enzyme that breaks down DNA strands in airway secretions, hydrolyzes the DNA present in sputum/mucus of CF patients, reducing viscosity in the lungs and promoting secretion clearance.
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