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See Latest ArticlesA randomised double blind trial of the effect of pre-emptive epidural ketamine on persistent pain after lower limb amputation
Pain, 02/14/08
Wilson JA et al. - The intrathecal/epidural technique used, with peri-operative sensory attenuation, may have reduced ongoing sensitisation, reducing the overall incidence of persistent pain. The improved short-term analgesia and reduced mechanical sensitivity in Group K may reflect acute effects of ketamine on central sensitisation. Longer term effects on mood were detected in Group K that requires further study.
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