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See Latest ArticlesClozapine-Induced Drop-Attack and Myoclonus
German Journal of Psychiatry, 01/22/08
Dhar R et al. - The types of seizures that can be precipitated by the administration of clozapine are varied, including tonic-clonic, myoclonic, and atonic seizures; and, myoclonic seizures may presage tonic-clonic seizures. Because of the eclectic pathogenesis of these diverse seizures, a broad-spectrum anticonvulsant agent is preferable. Valproic acid and lamotrigine are thus first-line drugs for the treatment of clozapine -induced seizures. Plasma clozapine levels and EEG findings may be of limited practical value in predicting or diagnosing seizures
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