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See Latest ArticlesCan Remifentanil Replace Nitrous Oxide During Anesthesia for Ambulatory Orthopedic Surgery with Desflurane and Fentanyl?
Anesthesia & Analgesia, 01/03/08
Mathews DM et al. - The administration of nitrous oxide (N2O) may be associated with side effects and toxicities. Remifentanil shares characteristics with N2O, including MAC-reducing and antinociceptive effects and a rapid decrease in clinical effect when discontinued...This study demonstrates that a remifentanil infusion of 0.085 microg.kg.min may be substituted for 66% N2O during desflurane/fentanyl anesthesia without any clinically significant change in outcome
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