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Risperidone for Treatment-Refractory Major Depressive Disorder
Annals of Internal Medicine, 11/02/07
Mahmoud, R.A., et al. - To assess whether augmentation therapy with risperidone reduces symptoms and increases response to antidepressant therapy and remission of depression in adults...Conclusion: Risperidone augmentation produced a statistically significant mean reduction in depression symptoms, substantially increased remission and response, and improved other patient- and clinician-rated measures
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