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A Phase 2 Feasibility Study of Sequential, Dose Intensive Chemotherapy to Treat Progressive Low-grade Gliomas in Children
Journal of Pediatric Hematology/Oncology, 09/14/07

Bruggers, C.S., et al. - Low-grade gliomas (LGGs) comprise nearly 35% of pediatric brain tumors and often occur in young children. Many cannot be resected and radiation therapy can be associated with excessive toxicity in children...Conclusion: Administration of sequential, dose intense chemotherapy was feasible and clinically tolerated. Concurrent anticonvulsant therapy limited dose intensity in 2 patients. Although efficacy appeared consistent with published larger series, small patient number in this study precludes definitive conclusions

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New agents for AML and MDS
Best Practice & Research: Clinical Haematology , 12/08/09

New advances in the treatment of adult chronic immune thrombocytopenic purpura: role of thrombopoietin receptor-stimulating agents
Biologics: targets & therapy, 12/08/09

Review: erythropoiesis-stimulating agents increase mortality in patients with cancer
Evidence-Based Medicine, 12/08/09

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Safety and pharmacokinetics of subcutaneous ceftriaxone administered with or without recombinant human hyaluronidase (rHuPH20) versus intravenous ceftriaxone administration in adult volunteers
Current Medical Research and Opinion, 12/08/09

Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: A double- blind, randomized, multicentre, placebo-controlled trial
Amyotrophic Lateral Sclerosis, 12/07/09

Potential interactions between cilostazol and probucol: A two-part, single-dose, open-label study in healthy Korean male volunteers
Clinical Therapeutics, 12/07/09

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