Action of Linezolid or Vancomycin on Biofilms in Ventriculoperitoneal Shunts In Vitro

Antimicrobial Agents and Chemotherapy, 05/31/2012

Neither vancomycin at concentrations achievable by intrathecal administration nor linezolid was able to eradicate enterococcal biofilms. It is hoped that these in vitro results will stimulate further clinical trials with linezolid, avoiding surgical shunt removal.

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