A simplified mechanistic algorithm for treating resistant hypertension: efficacy in a retrospective study

The Journal of Clinical Hypertension, 05/04/2012

The most frequent medication adjustments were addition of a potassium–sparing diuretic in 16 (67%), doxazosin in 9 (37.5%), and replacing a metabolized with a nonmetabolized β–blocker in 6 (25%). The authors conclude that treatment based on this algorithm can both simplify and improve the management of resistant hypertension and merits further evaluation in prospective studies.

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