High expression of TIMP-1 in human breast cancer tissues is a predictive of resistance to paclitaxel-based chemotherapy

Medical Oncology, 05/03/2012

The data showed that elevated tumor tissue Tissue inhibitor of metalloproteinases–1 (TIMP–1) levels were significantly associated with a poor response to paclitaxel–based chemotherapy, and TIMP–1 might be a potential biomarker for predicting response of breast cancer patients to paclitaxel–based chemotherapy.

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