Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells

British Journal of Cancer, 04/27/2012

On the basis of the expected impact of these two drugs on OCT–1 activity (OA), ibuprofen should be avoided in combination with imatinib. Further studies are warranted regarding the potential benefit of diclofenac to improve OA in a clinical setting.

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