Successful treatment of acyclovir-resistant herpes simplex virus type 2 proctitis with leflunomide in an HIV-infected man

Journal of Clinical Virology, 04/06/2012

Leflunomide has been shown to possess antiviral activity against several viruses. Herein authors describe a case of acyclovir resistant HSV–2 proctitis in an HIV patient successfully treated with leflunomide without significant side effects.

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