Effects of high-dose corticosteroids on post-traumatic inflammatory mediators Olav Reikeras et al. - This study shows that in traumatic injury there are generally higher local than systemic expressions of inflammatory mediators, and that the main anti-inflammatory effects of high-dose corticosteroids are suppression of systemic IL-6 and increased expressions of IL-10 and sTNF-R1, both systemically and locally. [more...]
