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The Combination of Doripenem and Colistin Is Bactericidal and Synergistic against Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae

Jernigan MG et al. – Among colistin– and pan–drug–resistant isolates, synergy was identified in 60 and 67%, respectively. All other combinations were inferior. Authors are currently evaluating the combination of doripenem and colistin as a frontline therapy for KPC infection. [more...]

Antimicrobial Agents and Chemotherapy

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