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The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis

Chiu J et al. – Child–Pugh A and Child–Pugh class B (CPB) patients tolerated sorafenib similarly and derived similar clinical and progression–free survival benefit. Among CPB patients, most benefits were observed in patients with a score of 7. Nevertheless, CPB patients were more susceptible to developing cirrhotic complications, and thus more vigilant surveillance is needed. [more...]

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