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Articles: Drug Trials



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Disagreements in meta-analyses using outcomes measured on continuous or rating scales: observer agreement study
British Medical Journal, 09/08/09    Free full text
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Novel evidence-based systemic lupus erythematosus (sle) responder index described in peer reviewed publication as potentially significant advance in lupus drug development
Human Genome Sciences, 09/08/09    Free full text
Independent Review of E2100: A Phase III Trial of Bevacizumab Plus Paclitaxel Versus Paclitaxel in Women With Metastatic Breast Cancer
Journal of Clinical Oncology, 09/04/09
Early Postoperative Paclitaxel Followed by Concurrent Paclitaxel and Cisplatin With Radiation Therapy for Patients With Resected High-Risk Head and Neck Squamous Cell Carcinoma: Report of the Phase II Trial RTOG 0024
Journal of Clinical Oncology, 09/04/09
Phase I and Biomarker Study of ABT-869, a Multiple Receptor Tyrosine Kinase Inhibitor, in Patients With Refractory Solid Malignancies
Journal of Clinical Oncology, 09/04/09
Array BioPharma Announces Top-Line Results from Rheumatoid Arthritis Phase 2 Trial
Array BioPharma, 09/04/09    Free full text
Novartis MF59 adjuvanted cell culture-based vaccine shows strong immune response in A(H1N1) clinical trials
Novartis, 09/04/09    Free full text
Two-Year SYNTAX Data Show Comparable Safety Outcomes for Complex Patients Treated With TAXUS EXPRESS Stents and Bypass Surger
Boston Scientific, 09/03/09    Free full text
Video: MADIT-CRT Trial Results Provide Clinical Evidence That Cardiac Resynchronization Therapy Significantly Slows Heart Failure Progression
Boston Scientific, 09/02/09    Free full text
Biovail Announces Results from ACADIAs Phase III Trial of Pimavanserin in Parkinsons Disease Psychosis
BioVail Corporation, 09/02/09    Free full text
FDA Advisory Committee Recommends Randomized Trial to Support Proposed Indication for Clolar in Adult AML
Genzyme, 09/02/09    Free full text
Shire Completes Submission of NDA for velaglucerase alfa for Type 1 Gaucher disease and Reports Positive Results for Remaining Two Phase III Trials
Shire, 09/02/09
Pharmacoeconomic Analysis of Reported Use of ENTEREG (alvimopan) Published in American Journal of Health-System Pharmacy
Adolor Corporation, 09/01/09    Free full text
Cytokinetics Presents Phase IIa Clinical Trials Data Relating to Omecamtiv Mecarbil at the European Society of Cardiology Congress 2009
Cytokinetics, 09/01/09    Free full text
Takeda Initiates Cardiovascular Outcomes Trial for Alogliptin, An Investigational Treatment for Type 2 Diabetes
Takeda Pharmaceuticals North America, 08/31/09
A substantial and confusing variation exists in handling of baseline covariates in randomized controlled trials: a review of trials published in leading medical journals
Journal of Clinical Epidemiology, 08/31/09
Trial sample size, but not trial quality, is associated with positive study outcome
Journal of Clinical Epidemiology, 08/31/09
Phase III head to head trial showed ticagrelor reduced cardiovascular death and heart attacks over clopidogrel in acute coronary syndromes patients
AstraZeneca, 08/31/09    Free full text
Bayer Completes Enrollment into Major Phase III Study with Rivaroxaban
BayNews International, 08/31/09    Free full text
Data from largest GOLD Stage II patient population treated with tiotropium highlight the benefits of earlier treatment of COPD
Boehringer Ingelheim, 08/31/09    Free full text

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