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The Best of 2009
D Scott Cunningham MD, PhD, MDLinx Oncology
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Articles: Basic Science



Latest (2) Month's Top Read Top 50 of Year  
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Prior Articles


Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis
Pharmacogenetics and genomics, 11/23/09
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Protein Kinase A Activation Confers Resistance to Trastuzumab in Human Breast Cancer Cell Lines
Clinical Cancer Research, 11/20/09
Relationship between Passive Permeability, Efflux, and Predictability of Clearance from in vitro Metabolic Intrinsic Clearance
Drug Metabolism and Disposition, 11/20/09
Human Cytochrome P450 Oxidoreductase Deficiency Caused by the Y181D Mutation: Molecular Consequences & Rescue of Defect
Drug Metabolism and Disposition, 11/20/09
If the KI is defined by the free energy of binding to P-gp, what kinetic parameters define the IC50 for the MDCKII-hMDR1 confluent cell monolayer
Drug Metabolism and Disposition, 11/20/09
Coupling of LC-MS/MS and LC-SPE-NMR techniques for the structural identification of metabolites following in vitro biotransformation of SUR1-selective KATP channel openers
Drug Metabolism and Disposition, 11/20/09
Time-dependent Inhibitory Effects of FK1706, a Novel Non-immunosuppressive Immunophilin Ligand, on CYP3A4/5 Activity in Humans in Vivo and in Vitro
Drug Metabolism and Disposition, 11/20/09
The Ethanol Metabolite Acetaldehyde Increases Paracellular Drug Permeability In Vitro and Oral Bioavailability In Vivo
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
Cyanide-induced Apoptosis of Dopaminergic Cells is Promoted by BNIP3 and Bax Modulation of Endoplasmic Reticulum-Mitochondrial Ca2+ Levels
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
Inhibition of Delayed-Type Hypersensitivity by Cucurbitacin R Through the Curbing of Lymphocyte Proliferation and Cytokine Expression by Means of NFAT Translocation to the Nucleus
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
Nicotine Exacerbates Brain Edema during in vitro and in vivo Focal Ischemic Conditions
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
Sigma-1 receptors regulate Bcl-2 expression by ROS-dependent transcriptional regulation of NF-kB
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
Endogenous Nitric Oxide Contributes to Bradykinin-Stimulated Glucose Uptake but Attenuates Vascular t-PA Release
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
NF546 is a non-nucleotide P2Y11 agonist and stimulates release of IL-8 from human monocyte-derived dendritic cells
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
Pharmacological Characterization of Human Incretin Receptor Missense Variants
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
Influence of cyclooxygenase inhibitors on the function of the prostaglandin transporter OATP2A1 expressed in human gastroduodenal mucosa
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
Dysopsonin Activity of Serum DNA-Binding Proteins Favorable for Gene Delivery
Journal of Pharmacology and Experimental Therapeutics, 11/20/09
A Comparison of the Role of PPAR and RAR on CYP26 Regulation
Molecular Pharmacology, 11/20/09
A novel multilevel statistical method for the study of the relationships between multireceptorial binding affinity profiles and in vivo endpoints
Molecular Pharmacology, 11/20/09
Epigallocatechin-3-gallate inhibits osteoclastogenesis by down-regulating c-Fos expression and suppressing the NF-kB signal
Molecular Pharmacology, 11/20/09

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Indexed Journals: Expert Opinion in Pharmacotherapy, Formulary, U.S.Pharmacist more...
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