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Johnson JA et al. - Despite optimal dosing of HCTZ + atenolol, only two-thirds of the participants achieved BP control. In HCTZ/atenolol combination antihypertensive therapy, the order in which the drugs are initiated affects total BP lowering during the first 4–6 months of therapy.

Today in Cardiac/Hypertension...keeping you current

Evaluation of arterial stiffness in morning hypertension under high-dose valsartan compared to valsartan plus low-dose diuretic
Hypertension Research, 12/17/09

Telmisartan/amlodipine: approved for high blood pressure
Formulary , 12/16/09

Clopidogrel Hypersensitivity: A Novel Multi-Day Outpatient Oral Desensitization Regimen
Annals of Pharmacotherapy, 12/16/09

Today in Drug Interactions...keeping you current

Acetazolamide and midazolam act synergistically to inhibit neuropathic pain
Pain, 12/16/09

Cyclosporine Versus Tacrolimus in Immunosuppressive Maintenance Regimens in Renal Transplants in Brazil: Survival Analysis from 2000 to 2004
Annals of Pharmacotherapy, 12/16/09

'Party pill' drugs - BZP and TFMPP
New Zealand Medical Journal, 12/14/09