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See Latest ArticlesBehavioral effects of GHB, its precursor GBL, and GABAB receptor agonists: time course, and differential antagonism by the GABAB receptor antagonist CGP35348
Journal of Pharmacology and Experimental Therapeutics, 06/30/09
Koek W et al. - This finding is further evidence that the GABAB receptor mechanisms mediating the effects of GHB and prototypical GABAB receptor agonists are not identical. A better understanding of the similarities and differences between these mechanisms, and their involvement in the therapeutic effects of GHB and baclofen, could lead to more effective medications with fewer adverse effects.
Today in Basic Science...keeping you current
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No evidence for functional selectivity of proxyfan at the human histamine H3-receptor coupled to defined Gi/Go protein heterotrimers
Journal of Pharmacology and Experimental Therapeutics, 12/07/09
Influence of Lipophilicity on Drug Partitioning into Sclera, Choroid-RPE, Retina, Trabecular Meshwork, and Optic Nerve
Journal of Pharmacology and Experimental Therapeutics, 12/07/09
Effect of nicotine on advanced glycation end products-induced immune response in human monocytes
Journal of Pharmacology and Experimental Therapeutics, 12/07/09
Today in Neuro/Psych pharmacology...keeping you current
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Kinematic improvement following Botulinum Toxin-A injection in upper limb spasticity due to stroke
Journal of Neurology, Neurosurgery, and Psychiatry , 12/07/09
Effects of Methylphenidate on Cerebral Glucose Metabolism in Patients With Impaired Consciousness After Acquired Brain Injury
Clinical Neuropharmacology, 12/07/09
Gabapentin Enacarbil in Restless Legs Syndrome: A Phase 2b, 2-Week, Randomized, Double-Blind, Placebo-Controlled Trial
Clinical Neuropharmacology, 12/07/09
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