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Jonas DE et al. - Recent studies have reported that polymorphisms in CYP4F2 might account for between 2 and 7% of the variation. Several prospective studies have evaluated genotype-guided dosing, but these have found negative results or were poorly designed.

Today in Basic Science...keeping you current

Bupivacaine Inhibits Glutamatergic Transmission in Spinal Dorsal Horn Neurons
Anesthesiology, 12/11/09

Expectations, validity, and reality in pharmacogenetics
Journal of Clinical Epidemiology, 12/11/09

Inhibitory effects of 1,3-thiazine derivatives on melanogenesis
Journal of Pharmacy and Pharmacology, 12/10/09

Today in Dosing...keeping you current

Abbott Seeks FDA Approval of New Dosage Strengths of SIMCOR
Abbott, 12/11/09

Voriconazole Pharmacokinetics and Pharmacodynamics in Children
Clinical Infectious Diseases, 12/11/09

Congenital abnormalities in children of 43 pregnant women who attempted suicide with large doses of nitrazepam
Pharmacoepidemiology and Drug Safety, 12/09/09