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Glycosylphosphatidylinositols are potential targets for the development of novel inhibitors for aerolysin-type of pore-forming bacterial toxins
Medicinal Research Reviews, 06/29/09
Wu Q et al. - This review has summarized the reported evidences supporting the GPI-dependent pore-forming mechanism for aerolysin-type of toxins and analyzed the possibility of targeting this unique process for the design and development of novel GPI-based inhibitors for these pore-forming bacterial toxins.
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