Your Article Summary
See Latest ArticlesLevetiracetam Induced Interstitial Nephritis and Renal Failure
Pediatric Neurology , 06/25/09
Hurwitz KA et al. - A 17-year-old girl who had started on levetiracetam because of new onset partial complex seizures developed acute renal failure and biopsy-confirmed interstitial nephritis 10 days after starting the drug. She made a complete and rapid recovery after discontinuation of levetiracetam and administration of oral corticosteroids. Levetiracetam, known to be predominantly excreted by the kidneys, has not previously been reported to cause significant renal complications in children. Children taking levetiracetam who present with abdominal pain, malaise, vomiting, oliguria, rash, or urticaria may require screening laboratory evaluation for potential renal adverse effects.
Related Articles
Acute renal failure from nitrofurantoin-induced acute granulomatous interstitial nephritis
QJM: An International Journal of Medicine, 10/16/09
Relevance Score: 80%
Drug-induced interstitial nephritis in a child with idiopathic nephrotic syndrome
Saudi Journal of Kidney Diseases and Transplantation, 10/30/09
Relevance Score: 79%
Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism
Heart And Circulatory Physiology, 11/12/09
Relevance Score: 67%
Interstitial pneumonia probably associated with sorafenib treatment: An alert of an adverse event
Lung Cancer, 11/16/09
Relevance Score: 66%
Effect of hyperinsulinemia and very-low-calorie diet on interstitial cytokine levels in subcutaneous adipose tissue of obese women
Endocrinology and Metabolism, 11/02/09
Relevance Score: 65%
Today in Adverse Drug Reactions...keeping you current
Receive free subspecialty "5-minute updates" via email
Cytidine Deaminase Residual Activity in Serum Is a Predictive Marker of Early Severe Toxicities in Adults After Gemcitabine-Based Chemotherapies
Journal of Clinical Oncology, 12/04/09
Birth defects in the sons and daughters of women who were exposed in utero to diethylstilbestrol (DES)
International Journal of Andrology, 12/04/09
Atazanavir-Associated Choledocholithiasis Leading to Acute Hepatitis in an HIV-Infected Adult
Annals of Pharmacotherapy, 12/03/09
Today in Neuro/Psych pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Antiepileptics in brain metastases: safety, efficacy and impact on life expectancy
Journal of Neuro-Oncology, 12/04/09
Combination therapy of 17(beta)-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke
Journal of Pharmacology and Experimental Therapeutics, 12/04/09
Glutamatergic (N-methyl-D-aspartate receptor) hypofrontality in schizophrenia: Too little juice or a miswired brain
Molecular Pharmacology, 12/04/09