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A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain
Current Medical Research and Opinion, 06/29/09
Daniels S et al. - Clinically meaningful and statistically significant improvements were observed with tapentadol IR 50mg and 75mg compared with placebo for the relief of moderate-to-severe acute pain after orthopedic surgery. Tapentadol IR 50mg and 75mg were non-inferior to oxycodone HCl IR 10mg for the treatment of acute pain based on the primary efficacy endpoint of SPID48 and the pre-specified margin of 48 points.
Today in Drug Interactions...keeping you current
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An evidence-based assessment of the clinical significance of drug-drug interactions between disease-modifying antirheumatic drugs and non-antirheumatic drugs according to rheumatologists and pharmacists
Clinical Therapeutics, 10/15/09
Meta-analysis of doripenem vs comparators in patients with pseudomonas infections enrolled in four phase III efficacy and safety clinical trials
Current Medical Research and Opinion, 10/27/09
Quality of Life Improvements Attributed to Combination Therapy with Oral and Topical Mesalazine in Mild-to-Moderately Active Ulcerative Colitis
Digestion, 10/15/09
Today in Other Drugs...keeping you current
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Doxycycline for osteoarthritis of the knee or hip
Cochrane Reviews, 10/23/09
Safety and efficacy of testosterone gel in the treatment of male hypogonadism
Clinical Interventions in Aging, 10/12/09
Biphasic effects of hormone treatment on risk of cardiovascular disease
Sexuality, Reproduction & Menopause, 10/20/09
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