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A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain
Current Medical Research and Opinion, 06/29/09

Daniels S et al. - Clinically meaningful and statistically significant improvements were observed with tapentadol IR 50mg and 75mg compared with placebo for the relief of moderate-to-severe acute pain after orthopedic surgery. Tapentadol IR 50mg and 75mg were non-inferior to oxycodone HCl IR 10mg for the treatment of acute pain based on the primary efficacy endpoint of SPID48 and the pre-specified margin of 48 points.

Today in Drug Interactions...keeping you current

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