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Veitch ZW et al. - The authors show for the first time that a variety of genes (particularly redox genes such as AKR1C2 and AKR1C3) can be temporally and causally correlated with the acquisition of anthracycline resistance in breast tumor cells.

Today in Chemotherapy/Oncology...keeping you current

Valproic acid restores ERalpha and antiestrogen sensitivity to ERalpha-negative breast cancer cells
Molecular and Cellular Endocrinology, 11/25/09

N2 Disease in Patients With Head and Neck Squamous Cell Cancer Treated With Chemoradiotherapy
Archives of Otolaryngology, 11/25/09

Salvage treatment with upfront melphalan 100 mg/m2 and consolidation with novel drugs for fulminant progression of multiple myeloma
Annals of Hematology, 11/24/09

Today in Dosing...keeping you current

Drug-Drug Interaction Between Itraconazole and the Protease Inhibitor Lopinavir/Ritonavir
Annals of Pharmacotherapy, 11/25/09

Impact of pharmaceutical dosage form on stability and dissolution of roxithromycin
Central European Journal of Medicine, 11/24/09

Postoperative analgesia with minidose intrathecal morphine for bipolar hip prosthesis in extremely elderly patients
Journal of Anesthesia, 11/24/09

Today in Drug Resistance...keeping you current

Risk Factors Associated with Methicillin Resistance among Staphylococcus aureus Infections in Veterans
Infection Control and Hospital Epidemiology, 11/25/09

Antiretroviral Drug-Resistant Mutations at Baseline and at Time of Failure of Antiretroviral Therapy in HIV Type 1-Coinfected TB Patients
AIDS Research and Human Retroviruses, 11/24/09

Protein Kinase A Activation Confers Resistance to Trastuzumab in Human Breast Cancer Cell Lines
Clinical Cancer Research, 11/20/09

Today in Other Drugs...keeping you current

Persistence with injectable antidiabetic agents in members with type 2 diabetes in a commercial managed care organization
Current Medical Research and Opinion, 11/25/09

Anti-relapse medications: Preclinical models for drug addiction treatment
Pharmacology & Therapeutics, 11/25/09

Glibenclamide-related excess in total and cardiovascular mortality risks: Data from large Ukrainian observational cohort study
Diabetes Research and Clinical Practice, 11/25/09