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Aspirin plus extended-release dipyridamole and clopidogrel were similarly effective for preventing recurrent stroke
Evidence-Based Medicine, 06/10/09
Sacco RL - Rates of recurrent stroke were similar in the aspirin + ERDP and clopidogrel groups, although the criterion for non-inferiority was not met. Groups did not differ for the composite end point (13% in each group) or net risk of recurrent stroke or major bleeding event. Risk of intracranial haemorrhage was increased in the aspirin + ERDP group. In patients with ischaemic stroke, aspirin plus extended-release dipyridamole and clopidogrel resulted in similar rates of recurrent stroke.
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