Upper Urinary Tract Infections Are Associated with RANTES Promoter Polymorphism

The Journal of Pediatrics, 10/04/2010

The authors evaluated the association between MCP–1, CCR2, RANTES, and CCR5 gene polymorphisms and upper urinary tract infection in 273 children recruited in Northeast Italy. Statistical analysis of RANTES–403 G>A genotype frequencies showed that children carrying the RANTES–403 G allele are at higher risk for urinary tract infection, irrespective of vesicoureteral reflux.

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