Upper Urinary Tract Infections Are Associated with RANTES Promoter Polymorphism
The Journal of Pediatrics, 10/04/2010
Centi S et al. – The authors evaluated the association between MCP–1, CCR2, RANTES, and CCR5 gene polymorphisms and upper urinary tract infection in 273 children recruited in Northeast Italy. Statistical analysis of RANTES–403 G>A genotype frequencies showed that children carrying the RANTES–403 G allele are at higher risk for urinary tract infection, irrespective of vesicoureteral reflux.