Cortisol as a biomarker of obstructive sleep apnea
As reported in Pediatric Pulmonology, salivary cortisol has an increased diurnal variation in children with mild or moderate-to-severe obstructive sleep apnea, while no changes in α-amylase were detected.
Procalcitonin predicts serious bacterial infections in children
As reported in Academic Emergency Medicine, elevated procalcitonin levels predicted serious bacterial infections in febrile children ≤ 36 months of age better than elevated white blood cell counts, elevated neutrophil counts, and elevated absolute band count.
Narrow-spectrum antibiotics recommended for CAP in children
As reported in Pediatrics, narrow-spectrum antibiotics yielded similar outcomes in children with community-acquired pneumonia (CAP) to broad-spectrum antibiotics. The study was conducted in 4 hospital and involved 492 patients between 2 months and 18 years with a discharge diagnosis of CAP. Other than a 10-hour decrease in length of stay in the narrow-spectrum antibiotic groups, the outcomes were similar between the narrow- and broad-spectrum antibiotic groups.