Exclusive content related to your pediatric, neonatal and adolescent patients is now available on MDLinx Pediatrics! Not only can you find numerous clinical pearls taken from recent daily competitive and Physician Review quizzes from the Smartest Pediatrician, but also a shortcut to keeping current with the highlights written by D. Scott Cunningham, MD, PhD, for the “can’t miss” articles published in your field. MDLinx Pediatrics is a premier service, complimentary for healthcare professionals, that sorts, ranks and summarizes the literature that’s relevant to your specialty and subspecialty. From adolescent medicine to radiology, neonatology to pediatric surgery, we have the coverage you need to stay on top of the ever-changing practice of pediatric medicine.
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1 A Health-Care System Perspective on Implementing Genomic Medicine: Pediatric Acute Lymphoblastic Leukemia as a Paradigm Clinical Pharmacology & Therapeutics, May 18, 2013 Review Article
2 The Childhood Leukemia International Consortium Cancer Epidemiology, May 18, 2013 Review Article
3 What is the relevance of Ikaros gene deletions as prognostic marker in pediatric Philadelphia negative B-cell precursor acute lymphoblastic leukemia? Full Text Haematologica, May 18, 2013 Clinical Article
4 Symptomatic osteonecrosis in childhood leukemia survivors: prevalence, risk factors and impact on quality of life in adulthood Full Text Haematologica, May 18, 2013 Clinical Article
5 High modal number and triple trisomies are highly correlated favorable factors in childhood B-cell precursor high hyperdiploid acute lymphoblastic leukemia treated according to the NOPHO ALL 1992/2000 protocols Full Text Haematologica, May 18, 2013 Clinical Article
6 Absolute lymphocyte count is associated with minimal residual disease level in childhood B-cell precursor acute lymphoblastic leukemia Leukemia Research, May 18, 2013 Clinical Article
7 Treatment for hepatitis C virus-induced portal hypertension in leukemic children Medical Oncology, May 18, 2013 Clinical Article
8 NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia Genes, Chromosomes and Cancer, May 18, 2013 Clinical Article
9 Next-generation-sequencing-based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia Genes, Chromosomes and Cancer, May 18, 2013 Clinical Article
10 The treatment of children suffering from chronic myelogenous leukemia: A comparison of the result of treatment with imatinib mesylate and allogeneic hematopoietic stem cell transplantation Pediatric Transplantation, May 18, 2013 Review Article
11 Role of NOS3 DNA Variants in Externalizing Behavioral Problems Observed in Childhood Leukemia Survivors Journal of Pediatric Hematology/Oncology, May 18, 2013 Clinical Article
12 NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern Leukemia, May 18, 2013 Review Article
13 Physical Performance of Nontransplanted Childhood ALL Survivors is Comparable to Healthy Controls Journal of Pediatric Hematology/Oncology, May 18, 2013 Clinical Article
14 Individual Tumor Response Testing in Multiple Relapsed Acute Myeloid Leukemia in Children Anticancer Research, May 18, 2013 Clinical Article
15 Allogeneic Hematopoietic Cell Transplantation in First Remission Abrogates Poor Outcomes Associated with High-Risk Pediatric Acute Myeloid Leukemia Biology of Blood and Marrow Transplantation, April 23, 2013 Clinical Article
16 Feasibility of Reduced-Intensity Allogeneic Stem Cell Transplantation With Imatinib in Children With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Pediatric Blood & Cancer, April 23, 2013
17 The BCL-2 Protein in Precursor B Acute Lymphoblastic Leukemia in Children Journal of Pediatric Hematology/Oncology, April 23, 2013 Clinical Article
18 Sarcopenia in Children With Acute Lymphoblastic Leukemia Journal of Pediatric Hematology/Oncology, April 23, 2013 Review Article
19 The BCL-2 Protein in Precursor B Acute Lymphoblastic Leukemia in Children Journal of Pediatric Hematology/Oncology, April 23, 2013 Review Article
20 BAX/BCL2 RMFI Ratio Predicts Better Induction Response in Pediatric Patients With Acute Myeloid Leukemia Pediatric Blood & Cancer, April 23, 2013 Review Article
21 Maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood acute lymphoblastic leukemia Leukemia Research, April 23, 2013 Clinical Article
22 Prognostic impact of absolute lymphocyte counts at the end of remission induction in childhood acute lymphoblastic leukemia Cancer, April 23, 2013 Clinical Article
23 MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia Clinical Cancer Research, April 23, 2013 Clinical Article
24 Childhood acute leukemia, maternal beverage intake during pregnancy, and metabolic polymorphisms Cancer Causes and Control, March 29, 2013 Clinical Article
25 High-risk childhood acute lymphoblastic leukemia in first remission treated with novel intensive chemotherapy and allogeneic transplantation Leukemia, March 29, 2013 Clinical Article
26 Slower processing speed after treatment for pediatric brain tumor and acute lymphoblastic leukemia Psycho-Oncology, March 29, 2013 Clinical Article
27 Outcome of transplantation for acute myelogenous leukemia in children with down syndrome Biology of Blood and Marrow Transplantation, March 29, 2013 Clinical Article
28 Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features Full Text Haematologica, March 29, 2013 Clinical Article
29 Early Cardiac Outcomes Following Contemporary Treatment for Childhood Acute Myeloid Leukemia: A North American Perspective Pediatric Blood & Cancer, March 29, 2013 Review Article
30 Hematopoietic stem cell transplantation for children with high risk acute lymphoblastic leukemia in first complete remission: a report from the AIEOP registry Full Text Haematologica, March 29, 2013 Clinical Article
31 Novel Susceptibility Variants at 10p12.31-12.2 for Childhood Acute Lymphoblastic Leukemia in Ethnically Diverse Populations Journal of the National Cancer Institute, March 29, 2013 Clinical Article
32 Anti-cancer effects of ginsenoside compound k on pediatric acute myeloid leukemia cells Cancer Cell International, March 29, 2013 Clinical Article
33 Simultaneous occurrence of ETV6-RUNX1 and BCR-ABL1 (e1a2) transcripts in a child with B-cell acute lymphoblastic leukemia Cancer Genetics, March 29, 2013
34 Induction mortality and resource utilization in children treated for acute myeloid leukemia at free-standing pediatric hospitals in the United States Cancer, March 3, 2013 Clinical Article
35 Obesity and Insulin Resistance in Pediatric Acute Lymphoblastic Leukemia Worsens During Maintenance Therapy Pediatric Blood & Cancer, March 3, 2013 Clinical Article
As published in Clinical Orthopedics and Related Research, elevated BMI is associated with fractures of the foot, ankle, knee, and leg (but not femur or hip) in children. In overweight, moderately obese, and extremely obese children, the ORs for fractures of the foot were 1.14, 1.23, and 1.42, respectively; fractures of the ankle, knee, and leg were 1.27, 1.28, and 1.51, respectively. Children 6-11 years of age were at highest risk.
Read the article summaryAs published in the Journal of Pediatric Hematology/Oncology, children with ?-thalassemia major (n=31; age range, 4-16 y) exhibit laboratory and ultrasound evidence of premature atherosclerosis. Specifically, total cholesterol, LDL-C, HDL-C, and nitrate/nitrite levels were decreased, and VLDL-C levels, chitotroisidase activity, and carotid IMT were increased in affected children.
Read the article summaryAs published in Pediatrics, adolescent girls (11-12 years of age) vaccinated with HPV were not shown to have increased sexual activity over 3 years of follow-up compared to non-vaccinated girls (adjusted incidence rate ratio = 1.29). Sexual activity was assessed based on pregnancy, STD testing or diagnosis, and contraceptive counseling.
Read the article summary1 Pacifier Restriction and Exclusive Breastfeeding Pediatrics, April 3, 2013 Review Article
2 Prebiotics in infants for prevention of allergy Cochrane Reviews, April 10, 2013 Review Article
3 The role of antibiotics in the treatment of acute rhinosinusitis in children: a systematic review Archives of Diseases in Childhood, March 8, 2013 Evidence Based Medicine
4 Association Between Total Duration of Breastfeeding and Iron Deficiency Pediatrics, April 16, 2013
5 Fish consumption in infancy and development of allergic disease up to age 12 y American Journal of Clinical Nutrition, April 11, 2013
6 Vitamin D and child health Archives of Diseases in Childhood, March 22, 2013 Review Article
7 Formula Selection for Management of Children with Cow Milk Allergy Influences the Rate of Acquisition of Tolerance: A Prospective Multicenter Study The Journal of Pediatrics, April 17, 2013 Review Article
8 Heliox Therapy in Bronchiolitis: Phase III Multicenter Double-Blind Randomized Controlled Trial Pediatrics, April 8, 2013
9 Reducing the Frequency of Acute Otitis Media by Individualized Care The Pediatric Infectious Disease Journal, April 23, 2013
10 Serum vitamin D levels in children with recurrent otitis media European Archives of Oto-Rhino-Laryngology, April 1, 2013
11 White Matter Injury in Preterm Infants: Could Human Milk Play a Role in Its Prevention? Advances in Neonatal Care, April 2, 2013 Review Article
12 Prenatal Maternal Bereavement and Congenital Heart Defects in Offspring: A Registry-Based Study Pediatrics, March 26, 2013 Review Article
13 Autism before diagnosis: crying, feeding and sleeping problems in the first two years of life Acta Pediatrica, March 14, 2013 Review Article
14 Clinical signs to identify late-onset sepsis in preterm infants European Journal of Pediatrics, April 2, 2013 Review Article
15 Probiotic effects in allergic disease Journal of Paediatrics and Child Health, April 19, 2013
16 Chronic Otitis Media in Children: An Evidence-Based Guide for Diagnosis and Management Clinical Pediatrics, April 11, 2013 Review Article
17 Predicting positive food challenges in children sensitised to peanuts/tree nuts Pediatric Allergy and Immunology, April 4, 2013
18 Infant feeding practices in the first 24 to 48 hours of life in healthy term infants Acta Pediatrica, April 15, 2013 Review Article
19 The relationship between visceral fat thickness and bone mineral density in sedentary obese children and adolescents BMC Pediatrics, March 21, 2013 Free full text Review Article
20 School-age Outcomes of Extremely Preterm or Extremely Low Birth Weight Children Pediatrics, April 3, 2013 Review Article
Indexed Journals in Pediatrics: Pediatrics International, Journal of Pediatrics, Current Pediatrics more
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