Pediatrics - Clinical Pharmacology News & Articles

Exclusive content related to your pediatric, neonatal and adolescent patients is now available on MDLinx Pediatrics! Not only can you find numerous clinical pearls taken from recent daily competitive and Physician Review quizzes from the Smartest Pediatrician, but also a shortcut to keeping current with the highlights written by D. Scott Cunningham, MD, PhD, for the “can’t miss” articles published in your field. MDLinx Pediatrics is a premier service, complimentary for healthcare professionals, that sorts, ranks and summarizes the literature that’s relevant to your specialty and subspecialty. From adolescent medicine to radiology, neonatology, pediatric surgery, to General Pediatric News, we have the coverage you need to stay on top of the ever-changing practice of pediatric medicine.

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Latest Full Text Articles (106) Focus on Neurologic Disorders

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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161 Complement disorders and hemolytic uremic syndrome Current Opinion in Pediatrics, March 22, 2013 Review Article

162 Acquired Bartter-Like Syndrome Associated with Colistin Use in a Preterm Infant Renal Failure, March 22, 2013 Clinical Article

163 Tolerability of Curcumin in Pediatric Inflammatory Bowel Disease: A Forced-Dose Titration Study Journal of Pediatric Gastroenterology and Nutrition, March 21, 2013 Clinical Article

164 Canakinumab in pediatric rheumatic diseases Expert Opinion on Biological Therapy, March 21, 2013 Clinical Article

165 Prevalence of renal dysfunction in tacrolimus-treated pediatric transplant recipients: A systematic review Pediatric Transplantation, March 21, 2013 Evidence Based Medicine Clinical Article

166 Heliox Therapy in Bronchiolitis: Phase III Multicenter Double-Blind Randomized Controlled Trial Pediatrics, March 20, 2013 Clinical Article

167 Racial Differences in Antibiotic Prescribing by Primary Care Pediatricians Pediatrics, March 20, 2013 Review Article

168 Glycopyrrolate and Theophylline for the Treatment of Severe Pallid Breath-holding Spells Pediatrics, March 20, 2013

169 Drug provocation tests in the diagnosis of hypersensitivity reactions to non-steroidal anti-inflammatory drugs in children Pediatric Allergy and Immunology, March 20, 2013 Clinical Article

170 Physical compatibility of various drugs with neonatal total parenteral nutrient solution during simulated Y-site administration American Journal of Health-System Pharmacy, March 20, 2013 Clinical Article

171 Intravenous Pamidronate in the Treatment of Severe Idiopathic Infantile Hypercalcemia Iranian Journal of Kidney Diseases, March 20, 2013 Clinical Article

172 Low Morbidity and Mortality in Children with Diabetic Ketoacidosis Treated with Isotonic Fluids The Journal of Pediatrics, March 19, 2013 Review Article

173 Off-label prescribing patterns of antiemetics in children: a multicenter study in Italy European Journal of Pediatrics, March 19, 2013 Review Article

174 Alemtuzumab induction in pediatric kidney transplantation Pediatric Transplantation, March 19, 2013 Review Article
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175 Landiolol hydrochloride infusion for treatment of junctional ectopic tachycardia in post-operative paediatric patients with congenital heart defect EP Europace, March 19, 2013 Clinical Article

176 Duration of empirical antibiotic therapy for infants suspected of early-onset sepsis Current Opinion in Pediatrics, March 18, 2013 Clinical Article

177 Comparative safety of selective serotonin reuptake inhibitors among pediatric users with respect to adverse cardiac events Pharmacoepidemiology and Drug Safety, March 18, 2013 Review Article

178 Enteral Feeding during Indomethacin and Ibuprofen Treatment of a Patent Ductus Arteriosus The Journal of Pediatrics, March 15, 2013 Review Article

179 Diverse Seizure Presentation of Acute Mycoplasma Pneumoniae Encephalitis Resolving With Immunotherapy Journal of Child Neurology, March 15, 2013

180 Medication-Related Emergency Department Visits and Hospital Admissions in Pediatric Patients: A Qualitative Systematic Review The Journal of Pediatrics, March 14, 2013 Evidence Based Medicine

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Clinical Pearls in Pediatrics

Having 2 or more siblings with autism spectrum disorder doubles the risk of ASD in younger children
Children with acute lymphoblastic leukemia are more susceptible to dental caries due to reduced salivary flow rate
Boys, but not girls, who are born post-term are at greater risk of adolescent obesity due to accelerated weight gain during childhood

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Pediatrics

Elevated BMI associated with lower extremity fractures in children

As published in Clinical Orthopedics and Related Research, elevated BMI is associated with fractures of the foot, ankle, knee, and leg (but not femur or hip) in children. In overweight, moderately obese, and extremely obese children, the ORs for fractures of the foot were 1.14, 1.23, and 1.42, respectively; fractures of the ankle, knee, and leg were 1.27, 1.28, and 1.51, respectively. Children 6-11 years of age were at highest risk.

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Children with ?-thalassemia major at risk for premature atherosclerosis

As published in the Journal of Pediatric Hematology/Oncology, children with ?-thalassemia major (n=31; age range, 4-16 y) exhibit laboratory and ultrasound evidence of premature atherosclerosis. Specifically, total cholesterol, LDL-C, HDL-C, and nitrate/nitrite levels were decreased, and VLDL-C levels, chitotroisidase activity, and carotid IMT were increased in affected children.

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HPV vaccination is not associated with increased sexual activity in adolescents

As published in Pediatrics, adolescent girls (11-12 years of age) vaccinated with HPV were not shown to have increased sexual activity over 3 years of follow-up compared to non-vaccinated girls (adjusted incidence rate ratio = 1.29). Sexual activity was assessed based on pregnancy, STD testing or diagnosis, and contraceptive counseling.

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Most Popular Pediatrics Articles

Last month's top read Top Articles of 2012

1 Association of CYP2C19 Polymorphisms and Lansoprazole-Associated Respiratory Adverse Effects in Children The Journal of Pediatrics, April 30, 2013

2 Incidence of Rash After Amoxicillin Treatment in Children With Infectious Mononucleosis Pediatrics, May 2, 2013

3 Does the Use of Antipyretics in Children Who Have Acute Infections Prolong Febrile Illness? A Systematic Review and Meta-Analysis The Journal of Pediatrics, May 10, 2013 Evidence Based Medicine

4 Use of Zoledronic Acid for Treatment of Chemotherapy Related Osteonecrosis in Children and Adolescents: A Retrospective Analysis Pediatric Blood & Cancer, May 16, 2013 Review Article

5 Dexibuprofen for fever in children with upper respiratory tract infection Pediatrics International, May 21, 2013

6 Safety of perinatal exposure to antiretroviral medications: developmental outcomes in infants The Pediatric Infectious Disease Journal, May 23, 2013 Review Article

7 Cold Preparation Use in Young Children After FDA Warnings: Do Concerns Still Exist? Clinical Pediatrics, April 1, 2013 Review Article

8 The safety of statins in children Acta Pediatrica, May 1, 2013 Review Article

9 Clinicians Views on Antiepileptic Medication Management in Nonepileptic Seizures Journal of Child Neurology, May 17, 2013

10 Auvi-Q Versus EpiPen: Preferences of Adults, Caregivers, and Children The Journal of Allergy and Clinical Immunology: In Practice, April 12, 2013

11 Influence of "GERD" Label on Parents’ Decision to Medicate Infants Pediatrics, May 6, 2013 Review Article

12 An update on pediatric hospital-based sedation Current Opinion in Pediatrics, May 14, 2013 Review Article

13 The clinical impact of switching attention hyperactivity disorder patients from OROS-MPH to Novo-MPH ER-C: A paediatric practice review Paediatrics & Child Health, February 20, 2013 Review Article

14 Efficacy and Safety of Whole Body Skin Cleansing With Chlorhexidine in Neonates—A Systemic Review The Pediatric Infectious Disease Journal, May 20, 2013 Evidence Based Medicine

15 Propranolol therapy of infantile hemangiomas: efficacy, adverse effects, and recurrence Pediatric Surgery International, March 28, 2013

16 Adrenocorticotropic Hormone for the Treatment of West Syndrome in Children Annals of Pharmacotherapy, April 29, 2013

17 High Rates of Resolution of Cholestasis in Parenteral Nutrition-Associated Liver Disease with Fish Oil-Based Lipid Emulsion Monotherapy The Journal of Pediatrics, December 10, 2012

18 Trough Concentrations of Vancomycin: Adult Therapeutic Targets Are Not Appropriate for Children The Pediatric Infectious Disease Journal, December 10, 2012

19 The utility of sildenafil in pulmonary hypertension: a focus on bronchopulmonary dysplasia Archives of Diseases in Childhood, May 7, 2013 Review Article

20 Serum ibuprofen levels of extremely preterm infants treated prophylactically with oral ibuprofen to prevent patent ductus arteriosus European Journal of Clinical Pharmacology, May 6, 2013

Indexed Journals in Pediatrics: Pediatrics International, Journal of Pediatrics, Current Pediatrics more

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Pediatrics - Clinical Pharmacology News & Articles

Articles

Clinical Pearls in Pediatrics

Highlights in Pediatrics

Elevated BMI associated with lower extremity fractures in children

Children with ?-thalassemia major at risk for premature atherosclerosis

HPV vaccination is not associated with increased sexual activity in adolescents

Most Popular Pediatrics Articles

Other Topics in Pediatrics