Pediatrics - Clinical Pharmacology News & Articles

Exclusive content related to your pediatric, neonatal and adolescent patients is now available on MDLinx Pediatrics! Not only can you find numerous clinical pearls taken from recent daily competitive and Physician Review quizzes from the Smartest Pediatrician, but also a shortcut to keeping current with the highlights written by D. Scott Cunningham, MD, PhD, for the “can’t miss” articles published in your field. MDLinx Pediatrics is a premier service, complimentary for healthcare professionals, that sorts, ranks and summarizes the literature that’s relevant to your specialty and subspecialty. From adolescent medicine to radiology, neonatology, pediatric surgery, to General Pediatric News, we have the coverage you need to stay on top of the ever-changing practice of pediatric medicine.

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Latest Full Text Articles (106) Focus on Neurologic Disorders

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

801 Clonidine Extended-Release: In Attention-Deficit Hyperactivity Disorder Pediatric Drugs, September 15, 2011

802 Antiretroviral Therapy for Children in Resource-Limited Settings: Current Regimens and the Role of Newer Agents Pediatric Drugs, September 15, 2011

803 Effects of the Limited English Proficiency of Parents on Hospital Length of Stay and Home Health Care Referral for Their Home Health Care-Eligible Children With Infections JAMA Pediatrics, September 14, 2011

804 Which is more effective in adolescent idiopathic scoliosis surgery: batroxobin, tranexamic acid or a combination Archives of Orthopaedic and Trauma Surgery, September 14, 2011 Clinical Article

805 Comparative Effectiveness of Antibiotic Treatment Strategies for Pediatric Skin and Soft-Tissue Infections Pediatrics, September 13, 2011

806 Increase in serotype 19A prevalence and amoxicillin non-susceptibility among paediatric Streptococcus pneumoniae isolates from middle ear fluid in a passive laboratory-based surveillance in Spain, 1997-2009 Full Text BMC Infectious Diseases, September 13, 2011

807 Efficient Intravenous Access Without Distress: A Double-blind Randomized Study of Midazolam and Nitrous Oxide in Children and Adolescents JAMA Pediatrics, September 12, 2011 Clinical Article

808 Prevalence of Polypharmacy Exposure Among Hospitalized Children in the United States JAMA Pediatrics, September 12, 2011

809 A decision aid for considering indomethacin prophylaxis vs. symptomatic treatment of PDA for extreme low birth weight infants Full Text BMC Pediatrics, September 7, 2011

810 A Long-Term Open-Label Extension Study Assessing Cognition and Behavior, Tolerability, Safety, and Efficacy of Adjunctive Levetiracetam in Children Aged 4 to 16 Years With Partial-Onset Seizures Journal of Child Neurology, September 7, 2011

811 Interictal Electroencephalography Can Influence Patient Selection for Methylprednisolone Therapy in Pediatric Refractory Epilepsy Journal of Child Neurology, September 7, 2011

812 Low plasma progranulin levels in children with autism Journal of Neuroinflammation, September 6, 2011 Clinical Article

813 Increasing Chloramphenicol Resistance in Streptococcus pneumoniae Isolates from Papua New Guinean Children with Acute Bacterial Meningitis Antimicrobial Agents and Chemotherapy, September 6, 2011

814 Erosive Potential of Sugar Free and Sugar Containing Pediatric Medicines Given Regularly and Long Term to Children The Indian Journal of Pediatrics, September 2, 2011

815 Long-term Efficacy of Low-dose Tricyclic Antidepressants for Children With Functional Gastrointestinal Disorders Journal of Pediatric Gastroenterology and Nutrition, September 1, 2011

816 Utility of intramuscular antibiotics for secondary prevention of early onset, asymptomatic 'suspected' neonatal sepsis Journal of Perinatology, September 1, 2011

817 Dosing Celecoxib in Pediatric Patients With Juvenile Rheumatoid Arthritis The Journal of Clinical Pharmacology, August 31, 2011 Clinical Article

818 Linezolid and Lactic Acidosis: A Role for Lactate Monitoring With Long-term Linezolid Use in Children The Pediatric Infectious Disease Journal, August 30, 2011

819 Meropenem/Clavulanate and Linezolid Treatment for Extensively Drug-resistant Tuberculosis The Pediatric Infectious Disease Journal, August 30, 2011

820 Vancomycin prescription in neonates and young infants: toward a simplified dosage ADC Fetal & Neonatal Edition, August 30, 2011

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Clinical Pearls in Pediatrics

Having 2 or more siblings with autism spectrum disorder doubles the risk of ASD in younger children
Children with acute lymphoblastic leukemia are more susceptible to dental caries due to reduced salivary flow rate
Boys, but not girls, who are born post-term are at greater risk of adolescent obesity due to accelerated weight gain during childhood

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Highlights in Pediatrics

Elevated BMI associated with lower extremity fractures in children

As published in Clinical Orthopedics and Related Research, elevated BMI is associated with fractures of the foot, ankle, knee, and leg (but not femur or hip) in children. In overweight, moderately obese, and extremely obese children, the ORs for fractures of the foot were 1.14, 1.23, and 1.42, respectively; fractures of the ankle, knee, and leg were 1.27, 1.28, and 1.51, respectively. Children 6-11 years of age were at highest risk.

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Children with ?-thalassemia major at risk for premature atherosclerosis

As published in the Journal of Pediatric Hematology/Oncology, children with ?-thalassemia major (n=31; age range, 4-16 y) exhibit laboratory and ultrasound evidence of premature atherosclerosis. Specifically, total cholesterol, LDL-C, HDL-C, and nitrate/nitrite levels were decreased, and VLDL-C levels, chitotroisidase activity, and carotid IMT were increased in affected children.

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HPV vaccination is not associated with increased sexual activity in adolescents

As published in Pediatrics, adolescent girls (11-12 years of age) vaccinated with HPV were not shown to have increased sexual activity over 3 years of follow-up compared to non-vaccinated girls (adjusted incidence rate ratio = 1.29). Sexual activity was assessed based on pregnancy, STD testing or diagnosis, and contraceptive counseling.

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Most Popular Pediatrics Articles

Last month's top read Top Articles of 2012

1 Association of CYP2C19 Polymorphisms and Lansoprazole-Associated Respiratory Adverse Effects in Children The Journal of Pediatrics, April 30, 2013

2 Incidence of Rash After Amoxicillin Treatment in Children With Infectious Mononucleosis Pediatrics, May 2, 2013

3 Does the Use of Antipyretics in Children Who Have Acute Infections Prolong Febrile Illness? A Systematic Review and Meta-Analysis The Journal of Pediatrics, May 10, 2013 Evidence Based Medicine

4 Use of Zoledronic Acid for Treatment of Chemotherapy Related Osteonecrosis in Children and Adolescents: A Retrospective Analysis Pediatric Blood & Cancer, May 16, 2013 Review Article

5 Dexibuprofen for fever in children with upper respiratory tract infection Pediatrics International, May 21, 2013

6 Safety of perinatal exposure to antiretroviral medications: developmental outcomes in infants The Pediatric Infectious Disease Journal, May 23, 2013 Review Article

7 Cold Preparation Use in Young Children After FDA Warnings: Do Concerns Still Exist? Clinical Pediatrics, April 1, 2013 Review Article

8 The safety of statins in children Acta Pediatrica, May 1, 2013 Review Article

9 Clinicians Views on Antiepileptic Medication Management in Nonepileptic Seizures Journal of Child Neurology, May 17, 2013

10 Auvi-Q Versus EpiPen: Preferences of Adults, Caregivers, and Children The Journal of Allergy and Clinical Immunology: In Practice, April 12, 2013

11 Influence of "GERD" Label on Parents’ Decision to Medicate Infants Pediatrics, May 6, 2013 Review Article

12 An update on pediatric hospital-based sedation Current Opinion in Pediatrics, May 14, 2013 Review Article

13 The clinical impact of switching attention hyperactivity disorder patients from OROS-MPH to Novo-MPH ER-C: A paediatric practice review Paediatrics & Child Health, February 20, 2013 Review Article

14 Efficacy and Safety of Whole Body Skin Cleansing With Chlorhexidine in Neonates—A Systemic Review The Pediatric Infectious Disease Journal, May 20, 2013 Evidence Based Medicine

15 Propranolol therapy of infantile hemangiomas: efficacy, adverse effects, and recurrence Pediatric Surgery International, March 28, 2013

16 Adrenocorticotropic Hormone for the Treatment of West Syndrome in Children Annals of Pharmacotherapy, April 29, 2013

17 High Rates of Resolution of Cholestasis in Parenteral Nutrition-Associated Liver Disease with Fish Oil-Based Lipid Emulsion Monotherapy The Journal of Pediatrics, December 10, 2012

18 Trough Concentrations of Vancomycin: Adult Therapeutic Targets Are Not Appropriate for Children The Pediatric Infectious Disease Journal, December 10, 2012

19 The utility of sildenafil in pulmonary hypertension: a focus on bronchopulmonary dysplasia Archives of Diseases in Childhood, May 7, 2013 Review Article

20 Serum ibuprofen levels of extremely preterm infants treated prophylactically with oral ibuprofen to prevent patent ductus arteriosus European Journal of Clinical Pharmacology, May 6, 2013

Indexed Journals in Pediatrics: Pediatrics International, Journal of Pediatrics, Current Pediatrics more

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Pediatrics - Clinical Pharmacology News & Articles

Articles

Clinical Pearls in Pediatrics

Highlights in Pediatrics

Elevated BMI associated with lower extremity fractures in children

Children with ?-thalassemia major at risk for premature atherosclerosis

HPV vaccination is not associated with increased sexual activity in adolescents

Most Popular Pediatrics Articles

Other Topics in Pediatrics