Cortisol as a biomarker of obstructive sleep apnea
As reported in Pediatric Pulmonology, salivary cortisol has an increased diurnal variation in children with mild or moderate-to-severe obstructive sleep apnea, while no changes in α-amylase were detected.
5-HT levels elevated in autism
As reported in European Neuropsychopharmacology, based on a meta-analysis of 22 studies, serotonin (5-HT) levels are significantly elevated in the whole blood of children with autism (OR = 4.6).
Narrow-spectrum antibiotics recommended for CAP in children
As reported in Pediatrics, narrow-spectrum antibiotics yielded similar outcomes in children with community-acquired pneumonia (CAP) to broad-spectrum antibiotics. The study was conducted in 4 hospital and involved 492 patients between 2 months and 18 years with a discharge diagnosis of CAP. Other than a 10-hour decrease in length of stay in the narrow-spectrum antibiotic groups, the outcomes were similar between the narrow- and broad-spectrum antibiotic groups.