Oral immunotherapy in hens egg-allergic children increases a hypo-proliferative subset of CD4+ T cells that could constitute a marker of tolerance achievement
Pediatric Allergy and Immunology, 07/27/2012
Fuentes–Aparicio V et al. – Acquisition of tolerance in children after oral immunotherapy is accompanied by a decrease in the TEM population and the increase in a particular subset of CD4+ T cells with a hypo–proliferative and non–reactive phenotype. This hypo–proliferative subset of cells could constitute a marker of the development of oral tolerance, and the study of this subset could contribute to the better understanding of the immune responses in allergic subjects.