Prognostic factors for treatment outcomes in transient tachypnea of the newborn
Pediatrics International, 07/05/2012
Bak SY et al. – Late–preterm, lower initial umbilical artery pH, and lower Apgar score at 1 min were independently associated with poor prognostic treatment outcomes in infants with Transient tachypnea of the newborn (TTN).Methods
- Data from 236 infants diagnosed with TTN during the study period were evaluated retrospectively.
- Logistic regression analyses were performed to select significant risk factor for prognosis (prolonged oxygen therapy, apply of mechanical ventilator, and prolonged hospital stay) of TTN among components of clinical variables.
- Of the 236 TTN infants, 111 (47.0%) infants were delivered by cesarean section (C/S) without labor, 29 (12.3%) infants were delivered by C/S with labor, and 96 (40.7%) were delivered by vaginal birth.
- Lower Apgar score at 1 min (odds ratio [OR]: 3.03, 95% confidence interval [CI]: 1.25-7.36) and lower umbilical artery pH (OR: 4.00, 95% CI 1.55-10.49) were associated with a significantly increased risk for mechanical ventilator care.
- Also, late-preterm (OR: 4.70, 95% CI: 2.11-10.49) was independently associated with risk of prolonged duration of hospital stay.