Increased RLS prevalence in children and adolescents with migraine: A case-control study
Seidel S et al. – This is the first study suggesting an association between restless legs syndrome (RLS) and migraine in the pediatric population. Future studies are needed to determine the extent of sleep disruption in children and adolescents with migraine and comorbid RLS.Methods
- Authors investigated 111 consecutive patients with a sole diagnosis of migraine with or without aura presenting to the Headache Unit at the Department of Child and Adolescent Psychiatry and 73 headache–free controls for the presence of RLS using a semistructured interview.
- In addition, authors assessed the level of daytime sleepiness by means of the Epworth sleepiness scale (ESS).
- A second group of headache–free controls was screened for the presence of RLS using an online questionnaire.
- The frequency of RLS in migraine patients was significantly higher than in controls (22% vs. 5% (p<0.001) and 8% (p<0.001)).