Growth and metabolic control in patients with type 1 diabetes and celiac disease: a longitudinal observational case-control study
Pediatric Diabetes,

Taler I et al. – Patients with type 1 diabetes (T1D) and celiac disease (CD) treated with GFD have growth and measures of metabolic control similar to those with T1D without CD. The decision whether asymptomatic celiac patients should be put on a GFD or only symptomatic patients has to be weighed against possible short– and long–term consequences of no intervention, and should be based on more evidence from larger randomized studies.

Methods
  • A longitudinal retrospective case–control design was used.
  • The medical files of 68 patients with T1D and duodenal–biopsy–confirmed CD were reviewed for data on weight, height, hemoglobin A1c (HbA1c), frequency of diabetic ketoacidosis (DKA), and severe hypoglycemic events before and after diagnosis and treatment of CD.
  • Findings were compared with 131 patients with T1D only matched for age, gender, and duration of diabetes.

Results
  • CD was diagnosed in 5.5% of all patients with T1D attending center during the study period; 26% of the patients with CD were symptomatic.
  • There were no significant differences in glycemic control or frequency of severe hypoglycemia or DKA events between the study and control groups.
  • Body mass index–standard deviation score (SDS), height–SDS, and HbA1c values were marginally but not significantly higher in the control than the study group and similar in subjects with CD with good or fair/poor adherence to a GFD throughout follow–up.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Pediatrics

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Pediatrics Articles

1 Rapid diagnostic tests for group a streptococcal pharyngitis: a meta-analysis Pediatrics, September 11, 2014    Evidence Based Medicine    Review Article

2 Fluticasone or montelukast in preschool wheeze: a randomized controlled trial Clinical Pediatrics, September 24, 2014    Clinical Article

3 Cow’s milk allergy: evidence-based diagnosis and management for the practitioner European Journal of Pediatrics, September 26, 2014    Review Article

4 Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis BMJ, August 20, 2014    Evidence Based Medicine    Clinical Article

5 Caffeine intake in children in the United States and 10-y trends: 2001–2010 American Journal of Clinical Nutrition, August 28, 2014    Clinical Article

6 Prenatal buprenorphine versus methadone exposure and neonatal outcomes: systematic review and meta-analysis American Journal of Epidemiology, September 10, 2014    Evidence Based Medicine    Review Article

7 Apgar score and the risk of cause-specific infant mortality: a population-based cohort study The Lancet, September 18, 2014    Evidence Based Medicine    Clinical Article

8 Association between gastroesophageal reflux and pathologic apneas in infants: a systematic review Neurogastroenterology & Motility, August 6, 2014    Review Article

9 Regular breakfast consumption and type 2 diabetes risk markers in 9- to 10-year-old children in the child heart and health study in england (CHASE): A cross-sectional analysis Full Text PLoS Medicine, September 8, 2014    Free full text    Clinical Article

10 Safety of vaccines used for routine immunization of US children: a systematic review Pediatrics, August 5, 2014    Evidence Based Medicine    Review Article

11 Generational shift in parental perceptions of overweight among school-aged children Pediatrics, September 17, 2014    Clinical Article

12 Human milk and neurodevelopment in children with very low birth weight: a systematic review Full Text Nutrition Journal, September 25, 2014    Free full text

13 Effects of single course and multicourse betamethasone prior to birth in the prognosis of the preterm neonates: A randomized, double-blind placebo-control clinical trial study Journal of Research in Medical Sciences, September 22, 2014    Clinical Article

14 Target fortification of breast milk: levels of fat, protein or lactose are not related Acta Pediatrica, September 15, 2014    Clinical Article

15 Childhood obesity: prevention and strategies of intervention. A systematic review of school-based interventions in primary schools Full Text Journal of Endocrinological Investigation, September 19, 2014    Free full text    Evidence Based Medicine    Review Article

16 Growth after adenotonsillectomy for obstructive sleep apnea: An RCT Pediatrics, August 7, 2014    Clinical Article

17 Cancer incidence rates and trends among children and adolescents in the United States, 2001-2009 Pediatrics, September 12, 2014    Clinical Article

18 Neonatal vitamin A supplementation associated with a cluster of deaths and poor early growth in a randomised trial among low-birth-weight boys of vitamin A versus oral polio vaccine at birth Full Text BMC Pediatrics, August 29, 2014    Free full text    Clinical Article

19 Effects of dietary interventions on neonatal and infant outcomes: a systematic review and meta-analysis American Journal of Clinical Nutrition, September 4, 2014    Evidence Based Medicine    Review Article

20 Exclusive breastfeeding is associated with reduced Cows milk sensitization in early childhood Pediatric Allergy and Immunology, September 3, 2014    Clinical Article

Indexed Journals in Pediatrics: Pediatrics International, Journal of Pediatrics, Current Pediatricsmore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close