RALLE Pilot: Response-guided Therapy for Marrow Relapse in Acute Lymphoblastic Leukemia in Children
Journal of Pediatric Hematology/Oncology, 05/11/2012
Saarinen–Pihkala UM et al. – An acute lymphoblastic leukemia (ALL) marrow relapse nonresponsive to steroids, vincristine, asparaginase, anthracyclines, and alkylating agents is uncommon, and these classic drugs can still be advocated for induction of ALL relapse. The problems lie in creating a consolidation capable of preventing particularly posttransplant relapses.