Nasal Intermittent Positive-Pressure Ventilation vs Nasal Continuous Positive Airway Pressure for Preterm Infants With Respiratory Distress Syndrome: A Systematic Review and Meta-analysis Full Text
JAMA Pediatrics,  Evidence Based Medicine

Meneses J et al. – Among preterm infants with respiratory distress syndrome, NIPPV decreases the need for invasive ventilation within the first 72hours of life compared with nasal continuous positive airway pressure (NCPAP). Trials are needed to assess whether nasal intermittent positive–pressure ventilation (NIPPV) minimizes the occurrence of bronchopulmonary dysplasia and other comorbidities.

Methods
  • MEDLINE, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, and clinicaltrials.gov were searched, as well as abstracts from meetings of the Pediatric Academic Societies.
  • Randomized controlled trials involving infants with respiratory distress syndrome who received NIPPV vs NCPAP.
  • Data were extracted on the use of NIPPV vs NCPAP.
  • Also extracted were data on the need for invasive ventilation within the first 72hours of life and the incidences of bronchopulmonary dysplasia, pneumothorax, necrotizing enterocolitis, and intraventricular hemorrhage, as well as the time to full feeds and the duration of hospital stay.

Results
  • Three trials were included (n=360).
  • A significant decrease in the need for invasive ventilation was found in the NIPPV group (risk ratio, 0.60; 95% CI, 0.43-0.83).
  • No difference between groups was found in the incidence of bronchopulmonary dysplasia (risk ratio, 0.56; 95% CI, 0.09-3.49).
  • No differences in the other outcomes were observed between the 2 groups.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access Full Text, PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Pediatrics

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Pediatrics Articles

1 Rapid diagnostic tests for group a streptococcal pharyngitis: a meta-analysis Pediatrics, September 11, 2014    Evidence Based Medicine    Review Article

2 Fluticasone or montelukast in preschool wheeze: a randomized controlled trial Clinical Pediatrics, September 24, 2014    Clinical Article

3 Cow’s milk allergy: evidence-based diagnosis and management for the practitioner European Journal of Pediatrics, September 26, 2014    Review Article

4 Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis BMJ, August 20, 2014    Evidence Based Medicine    Clinical Article

5 Caffeine intake in children in the United States and 10-y trends: 2001–2010 American Journal of Clinical Nutrition, August 28, 2014    Clinical Article

6 Prenatal buprenorphine versus methadone exposure and neonatal outcomes: systematic review and meta-analysis American Journal of Epidemiology, September 10, 2014    Evidence Based Medicine    Review Article

7 Apgar score and the risk of cause-specific infant mortality: a population-based cohort study The Lancet, September 18, 2014    Evidence Based Medicine    Clinical Article

8 Association between gastroesophageal reflux and pathologic apneas in infants: a systematic review Neurogastroenterology & Motility, August 6, 2014    Review Article

9 Regular breakfast consumption and type 2 diabetes risk markers in 9- to 10-year-old children in the child heart and health study in england (CHASE): A cross-sectional analysis Full Text PLoS Medicine, September 8, 2014    Free full text    Clinical Article

10 Safety of vaccines used for routine immunization of US children: a systematic review Pediatrics, August 5, 2014    Evidence Based Medicine    Review Article

11 Generational shift in parental perceptions of overweight among school-aged children Pediatrics, September 17, 2014    Clinical Article

12 Human milk and neurodevelopment in children with very low birth weight: a systematic review Full Text Nutrition Journal, September 25, 2014    Free full text

13 Effects of single course and multicourse betamethasone prior to birth in the prognosis of the preterm neonates: A randomized, double-blind placebo-control clinical trial study Journal of Research in Medical Sciences, September 22, 2014    Clinical Article

14 Target fortification of breast milk: levels of fat, protein or lactose are not related Acta Pediatrica, September 15, 2014    Clinical Article

15 Childhood obesity: prevention and strategies of intervention. A systematic review of school-based interventions in primary schools Full Text Journal of Endocrinological Investigation, September 19, 2014    Free full text    Evidence Based Medicine    Review Article

16 Growth after adenotonsillectomy for obstructive sleep apnea: An RCT Pediatrics, August 7, 2014    Clinical Article

17 Cancer incidence rates and trends among children and adolescents in the United States, 2001-2009 Pediatrics, September 12, 2014    Clinical Article

18 Neonatal vitamin A supplementation associated with a cluster of deaths and poor early growth in a randomised trial among low-birth-weight boys of vitamin A versus oral polio vaccine at birth Full Text BMC Pediatrics, August 29, 2014    Free full text    Clinical Article

19 Effects of dietary interventions on neonatal and infant outcomes: a systematic review and meta-analysis American Journal of Clinical Nutrition, September 4, 2014    Evidence Based Medicine    Review Article

20 Exclusive breastfeeding is associated with reduced Cows milk sensitization in early childhood Pediatric Allergy and Immunology, September 3, 2014    Clinical Article

Indexed Journals in Pediatrics: Pediatrics International, Journal of Pediatrics, Current Pediatricsmore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close